Intelligence / Retatrutide

Retatrutide

Under Review
Triple Agonist (GLP-1/GIP/Glucagon)
Schedule
S4
Under Review
Enforcement
Monitoring
Medium Risk
Providers
2
Access: Emerging
Key Facts
Schedule 4 - Prescription Only
Triple GLP-1/GIP/Glucagon receptor agonist
Not yet TGA-approved
Phase 3 trials ongoing globally
Grey market supply emerging in Australia

Overview

Retatrutide is a novel triple hormone receptor agonist targeting GLP-1, GIP, and glucagon receptors simultaneously. It is not yet TGA-approved and remains in Phase 3 clinical trials globally. Grey market supply has emerged in Australia.

Australian Scheduling

Schedule 4 (Prescription Only). Not yet TGA-approved or ARTG-listed. Under active regulatory monitoring. Grey market supply is under increasing scrutiny.

Access Pathway

Very limited legal prescription access through 2 identified providers. Most Australian supply is currently through grey market channels, which carries significant regulatory and quality risk.

Regulatory Notice

For informational purposes only. TGA scheduling may change without notice. All Schedule 4 peptides require a valid prescription from a registered Australian medical practitioner. This site does not sell, supply, or facilitate access to therapeutic goods. Data compiled from TGA SUSMP, public provider directories, and publicly available review platforms.

News & Updates20 items
Composition and Labelling Accuracy of Products Sold as Retatrutide in Australia
Drug Alcohol Rev1 Sept 2026
Disease-modifying anti-diabetic drugs (DMADDs): bridging the SIMPLE approach to disease interception.
Cardiovascular Diabetology26 Aug 2026
Online-Sourced Retatrutide Complicating Impending Diabetic Ketoacidosis in a Patient With Type 1 Diabetes and Concurrent Shigella Gastroenteritis
Cureus26 Aug 2026
GLP-1 and dual GIP/GLP-1 receptor agonists' psychopharmacology and putative neuropsychiatric associated effects: a Bradford Hill-informed, systematic, evaluation
Curr Psychiatry Rep21 Aug 2026
Retatrutide-Associated Improvements in Cardiovascular Risk Biomarkers in Adults With Obesity With or Without Type 2 Diabetes
Diabetes Obes Metab17 Aug 2026
What to know about retatrutide
Eli Lilly and Company13 Aug 2026
Comparative effects of semaglutide tirzepatide and retatrutide on renal fibrosis in UUO and aged mice
iScience13 Aug 2026
Retatrutide: Obesity drug opens to "compassionate use" in US after speculation Trump took it
BMJ7 Aug 2026
Integrating GLP-1 Receptor Agonists Into Dermatology Practice: Safety and Monitoring Strategies
Clin Dermatol6 Aug 2026
The role of GLP-1 and GIP receptor agonists in the treatment of diabetes and obesity
Pharmacol Res5 Aug 2026
Anti-Obesity Medications in Longevity and Aesthetic Medicine
Journal of Clinical Medicine3 Aug 2026
Beyond weight loss: multisystem benefits of obesity medications
Lancet Diabetes Endocrinol1 Aug 2026
Retatrutide effects on diabetic rats' cognition
Lab Anim (NY)1 Aug 2026
[An historical overview of GLP-1/GIP incretins. From hormone to "swiss-army knife" medications].
Biologie aujourd'hui31 July 2026
Glucagon-like peptide-1 and peptide YY multi-agonism with GEP44 to optimize weight loss and glycemic control while reducing gastrointestinal side effects: the future of anti-obesity pharmacotherapy?
Frontiers in endocrinology31 July 2026
Incretin analogues as cardiovascular agents: a state-of-the-art review.
Frontiers in endocrinology24 July 2026
Retatrutide and the urinary tract infection signal: Is the answer hidden in timing?
Eur J Intern Med23 July 2026
Lilly's triple agonist retatrutide successful in two additional Phase 3 obesity trials, delivering significant improvements in weight and A1C
Eli Lilly and Company23 July 2026
Development and validation of a multiplexed LC-HRMS method for nine GLP-1 receptor agonists and its pharmaceutical application.
Journal of chromatography. A21 July 2026
Influencers, suppliers warned as TGA cracks down on black-market peptides
Sky News Australia20 July 2026

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