Intelligence / Tirzepatide

Tirzepatide

Prescription Only
GLP-1/GIP Agonist
Schedule
S4
Prescription Only
Enforcement
Tightening
Medium Risk
Providers
8
Access: Emerging
Key Facts
Schedule 4 - Prescription Only
Dual GLP-1/GIP receptor agonist
Mounjaro is TGA-approved
Compounding pathway under review
Grey market supply increasing

Overview

Tirzepatide is a dual GLP-1/GIP receptor agonist. The branded product Mounjaro has received TGA approval in Australia. The compounding pathway for tirzepatide is currently under review, and grey market supply has been increasing.

Australian Scheduling

Schedule 4 (Prescription Only). Mounjaro is TGA-approved and ARTG-listed. Compounding pathway is under active regulatory review. The TGA is monitoring the grey market supply closely.

Access Pathway

Available through telehealth providers and compounding pharmacies, though fewer providers offer it compared to semaglutide. The compounding pathway may face restrictions. Grey market availability is increasing but carries significant risk.

Regulatory Notice

For informational purposes only. TGA scheduling may change without notice. All Schedule 4 peptides require a valid prescription from a registered Australian medical practitioner. This site does not sell, supply, or facilitate access to therapeutic goods. Data compiled from TGA SUSMP, public provider directories, and publicly available review platforms.

News & Updates20 items
Off-label GLP-1 receptor agonist and tirzepatide use for weight loss: patient safety and regulatory oversight
Annals of medicine and surgery (2012)15 July 2026
Case Report: Dramatic metabolic improvement with tirzepatide in a patient with acquired partial lipodystrophy following hematopoietic stem cell transplantation
Frontiers in endocrinology15 July 2026
Comparative effectiveness of tirzepatide and DPP-4 inhibitors in type 2 diabetes with heart failure
Diabetes & vascular disease research15 July 2026
Understanding reasons for initiation and experience with tirzepatide among individuals with obesity or overweight: PERCEPTIONS survey results
Obesity Pillars11 July 2026
Lower fall and femoral fracture risks with semaglutide and tirzepatide compared with DPP-4 inhibitors in older adults with type 2 diabetes
Osteoporosis International11 July 2026
Tirzepatide compared with semaglutide in obesity disease: a subpopulation analysis applying Japan Society for the Study of Obesity criteria in the global SURMOUNT-5 trial
Current Medical Research and Opinion11 July 2026
Influence without medical expertise: a social network analysis of Mounjaro discussions on X
Saudi Pharmaceutical Journal10 July 2026
Patterns of Use for GLP-1 Receptor Agonists in a Weight Management Cohort: A Military Health System Database Analysis of Active Duty Service Members From 2021 to 2025
Mil Med9 July 2026
Tirzepatide and risk of newly diagnosed aortic stenosis in patients with obesity: a multi-institutional real-world cohort study
BMC Cardiovascular Disorders9 July 2026
An Open-Label Tirzepatide Trial for Comorbid Obesity and Stimulant Use Disorder
ClinicalTrials.gov9 July 2026
Study of Tirzepatide for Recovery and Alcohol Use Management
ClinicalTrials.gov9 July 2026
Tirzepatide Titration to Reduce Side Effects in Individuals With Obesity
ClinicalTrials.gov8 July 2026
A Master Protocol Study (LY900038) of Multiple Intervention-Specific-Appendices (ISAs) in Adult Participants With Obesity or Overweight
Eli Lilly and Company7 July 2026
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
Eli Lilly and Company7 July 2026
A Study of Tirzepatide (LY3298176) Compared With Standard of Care in Adult Participants With Obesity and Without Diabetes (SURMOUNT-REAL UK)
Eli Lilly and Company7 July 2026
Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study
Eli Lilly and Company7 July 2026
Efficacy of tirzepatide versus SGLT2 inhibitors in metabolic dysfunction-associated steatotic liver disease (MASLD): a multicenter propensity-matched real-world study.
Hepatology international3 July 2026
GLP-1 Agonists and Risk of Atrial Fibrillation in Non-Dialysis Chronic Kidney Disease.
Cardiovascular drugs and therapy3 July 2026
Current Concepts in Perioperative Guidance and Outcomes in Hand Surgery Patients Taking Glucagon-Like Peptide-1 Receptor Agonists.
The Journal of hand surgery3 July 2026
Endotypic trait responses to 12-month tirzepatide treatment for an obese patient with obstructive sleep apnea
Obesity Facts30 June 2026

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